Why does the mouth taste bitter when it hurts?

    Why does the mouth taste bitter when it hurts? Bitter tongue is one of the complaints that is often experienced by someone who is sick, for example during a fever. This condition often makes it difficult for sufferers to eat, where the food they eat tastes strange and even tasteless.

    Fever is not a disease, but a sign of a problem in the body. There are so many health disorders that can cause fever. Such as viral or bacterial infections, poisoning, to cancer.

    Why does the mouth taste bitter when it hurts?

    Reporting from Nature, Saturday (29/4/2015) the researchers revealed that the sensory changes that occur when sick can be caused by proteins that trigger inflammation.

    In a study published in the journal Brain, Behavior, and Immunity in 2015, they said the cause of tongue pain when sick was influenced by a protein called tumor necrosis factor-alpha (TNF-alpha).

    People with infections, autoimmune diseases, or other inflammatory conditions have higher levels of TNF-alpha than healthy people.

    In addition, the protein has also been shown to reduce appetite so that patients tend to lack food intake.

    The research team from the Monell Chemical Senses Center in Philadelphia, Pennsylvania used genetically modified mice and ordinary mice to investigate the taste-related effect of TNF-alpha in a given solution.

    The results found that mice that could not produce TNF-alpha tended to react normally to solutions with sweet, sour, and salty tastes, but were less sensitive to bitter tastes.

    The team finally concluded that TNF-alpha only reacts in the sense of taste itself, and affects the perception of bitter taste in the mouth.

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    On the other hand, Wang and his team will also investigate whether high levels of TNF-alpha during illness make a person very sensitive to bitter tastes.

    In addition to inflammation or infection, as reported by Healthline Wednesday (6/11/2019), a bitter mouth is also experienced due to certain conditions, including:

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